The genetical and physiological effect of leptin gene on productive and reproductive traits of domestic animals

Document Type : Scientific-Extensional Article

Authors

1 M.Sc. Student of Animal Breeding and Genetics, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

2 Ph.D. Student of Animal and Poultry Breeding & Genetics, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

3 B.Sc. Student of Animal Science, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

4 Ph.D. Student of Animal Physiology, Department of Animal Science, College of Agriculture and Natural Resources, University of Tehran, Karaj, Iran

Abstract

The selection of superior bulls is traditionally based on the milk production of their Offspring, while the increases of milk production is associated with fertility reduction. The negative energy balance after gestation and during the milk production is the major reason for this fertility reduction. During this period, cows mobilize their body's fat sources, and the system prefer to use this energy for milk production rather that reproduction and immune system. The assumption that the hormones play an important role in restoring fertility following selection based on milk production have been much discussed in the recent years. Research have been conducted to identify a hormone that links the nutritional status with fertility in dairy cows. One of these hormones which has an important role is Leptin. This hormone is a protein consists of 167 amino acids with 16 kDa molecular weight that is encoded by the ob (Obesity) gene. It is mainly secreted by adipocyte cells in adipose tissue, which increases with increasing of the fat resources. It is involved in regulating food intake, energy balance, fertility, and immune system function.  Therefore, this paper was aimed to review the Leptin metabolism and its effect on productive and reproductive traits and in domestic animals.

Keywords

References

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