Importance of bacterial endotoxins in poultry farming

Document Type : Scientific-Extensional Article

Authors

1 Ph.D. in Animal Sciences, Director of Research and Development Unit, Sepidmakian Company, Rasht, Gilan, Iran

2 Ph.D. in Animal Sciences, Researcher of Research and Development Unit, Sepidmakian Company, Rasht, Gilan, Iran

3 M.Sc. in Poultry Nutrition, Department of Animal Science, Department of Animal Science, University of Gilan, Rasht, Gilan, Iran

10.22059/domesticsj.2024.376729.1150

Abstract

Endotoxin, a toxic compound of lipopolysaccharide (LPS) found in the outer membrane of gram-negative bacteria, it serves as a protector against environmental damage. Poultry is continuously exposed to lipopolysaccharides during their rearing period. In healthy birds, the intestinal epithelium, skin, or lungs serve as effective barriers, preventing the transfer of this toxin into the bloodstream. Endotoxins in animals are most commonly found in the intestine, where Gram-negative bacteria accumulate. If endotoxins enter the bloodstream, the immune system is chronically stimulated and by destroying intestinal cells, increasing oxidative stress factors and energy consumption to detoxify the body, it reduces the bird's productive performance. The purpose of this short review is to understand the structure and function of endotoxins, how they stimulate the immune system, its effect on poultry performance, and finally, to assess the methods for prevention and diagnosis in an endotoxin challenge.

Keywords

References

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Professional Journal of Domestic
Volume 24, Issue 2 - Serial Number 29
In Progress
September 2024
Pages 14-21

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